There are times when special vocal characteristics need to attract the attention of listeners and/or viewers particularly if there is a funny element involved. These are the times to you might consider using a ditzy voice.
A ditzy voice is the one that sounds eccenrically silly, goofy, even inane. The voice of the well-known TV actress Fran Drescher is often characterized as ditzy. It is a voice that is certain to attract attention, often testing the patience of the listeners. That is why it is mostly used with a good measure to make brief, punchy points. It often sounds silly and frivolous, but not necessarily connected to the content of the message in that manner.
Any audience that appreciates a good comedy elment is at the same time bound to appreciate a good, measured use of a ditzy voice. Sometimes such a voice expresses a humorous, comic message, but there are also times when it needs to point out the absurdity of certain situations. Besides comey, a ditzy voice is often used in commercials, but also in political ads.
A ditzy voice sounds as it is completely oblivious of a certain situation, or that it simply doesn't understand what is going on. It is bound to express the absurtity of a certain situation, but as if the voice itself doesn't comprehend what is really going on. A ditzy voice is sometimes used when it needs to express a situation when a person is intoxicated or not exactly one of the brightest around.